Hopkins was connected with the Fitzroy family and a personal friend of the 3rd Duke of Grafton. On 27 June 1755, when the 2nd Duke was alive, Hopkins wrote to Newcastle about a vacancy at Seaford:
On 26 Oct. 1775 Hopkins voted against the Address, yet retained his place until 1777. On 9 Dec. the King wrote to North:
In 1782-3 his conduct closely followed Grafton’s: he held office under Rockingham and Shelburne, but refused to join the Coalition in spite of his liking for Fox. He voted against the East India bill on 27 Nov. 1783, yet wrote to Grafton on 16 Dec.:
He died 19 Mar. 1799.
