O’Callaghan was thought by some contemporaries to be the younger brother of Cornelius O’Callaghan, 2nd Baron Lismore, but was in fact his uncle.
Defeated at Tregony in 1812, O’Callaghan recovered the seat in 1818 and continued steadily in the same political line, supporting the requisition to Tierney to lead the Whigs. He voted for Tierney’s censure motion, 18 May 1819. On 6 and 8 Dec. 1819 he voted for a limitation of the seditious meetings bill and on 14 Dec. against the seizure of arms bill. He retired in 1826. He died 14 Feb. 1836.
