Like his father, the master of University College, Oxford, who died in 1807 worth £100,000,
Wetherell contested Sudbury unsuccessfully in 1806 as an opponent of the Grenville ministry and was at first defeated at Shaftesbury on the patron’s interest in 1812:
Wetherell hoped to become a law officer of the crown as a reward for his services but was, he felt, unjustly neglected by administration: his defence of the radical Watson in 1817 by which he intended to ‘eclipse the crown lawyers, baffle the Home secretary, resist the chief justice and rebuke the prime minister’ made his point for him without getting him anywhere. In 1818 he was left without a seat; he had canvassed Hereford in January, but gave it up. He declined to become a candidate for Westminster at the general election and likewise for Sussex. Nor, as anticipated, did he offer in the Westminster by-election of 1819. But he was too formidable a figure to be ignored indefinitely. He died 17 Aug. 1846, ‘one of the last specimens of a thorough Tory of the oldest school ... a very learned man ... but ... one of the greatest slovens that ever walked’.
