Vaughan was a scion of the Golden Grove family which dominated Carmarthenshire politics during the early Stuart period. As a younger son his prospects were not promising, but he acquired local standing through his marriage to the heiress of Derwydd, Llandybie. His wife, Sage, had been married briefly to one of his cousins, and after her father’s death in around 1610 she came into sole possession of an estate of at least 600 acres.
The Vaughan family operated as a cohesive political bloc within Carmarthenshire, and Henry’s parliamentary career was doubtless promoted by his elder brother, Sir John*. Henry was also closely allied to another brother, Walter of Llanelli, and the pair operated as deputy coroners under Sir John in Kidwelly lordship, which was reputed to contain one third of the county’s freeholders.
In April 1620 Vaughan acquired a stake in the monopoly of the manufacture of coke from coal, along with the courtier (Sir) Giles Mompesson*, Walter Vaughan, Protheroe and local merchant Hugh Grundy, probably in the hope of utilizing the coal and mineral mines owned by the Vaughans in and around Llanelli.
In August 1623 Vaughan was chosen as mayor of Carmarthen, but this did not impede his election as borough Member the following February, a return which technically contravened the Commons’ ruling that mayors should not serve in Parliament. However, perhaps because the borough’s sheriffs had been returning officers at Carmarthen since 1614, the point was overlooked.
Vaughan was returned for Carmarthen Boroughs for the fourth consecutive time in 1626, but once again he failed to make an impression on the parliamentary records. He evidently attended the Commons, however, as he later recalled missing an affray at Carmarthen due to his absence at Westminster.
By 1628 Vaughan leased six Carmarthenshire rectories from Lord Henry Percy*; in the 1640s his one-time partner in the charcoal patent, Hugh Grundy, accused him of paying inadequate stipends to his curates.
In his will of 27 Nov. 1660, Vaughan assigned lands to raise portions for his unmarried daughters, and appointed his eldest surviving son, (Sir) Henry†, as his executor. He was dead by 5 Jan. 1661, when an inventory of his goods was made at Derwydd.
