Twyneho came from a branch of a West Country family that had produced a knight of the shire for Dorset in 1478. His father and uncle both served the Catholic Lords Paget, and his uncle was removed as a magistrate in 1587 for being ‘backward in religion’.
Twyneho left little trace on the records of the 1604 session, being named to just two committees, these being for bills to regulate the making of barrels (24 Apr.) and promote archery (7 June). In 1605, presumably with Dorset’s approval, he secured a patent for the manufacture of smalt, a dyestuff also known as ‘blue starch’, at a rent of £20 p.a., which was investigated as a monopoly during the 1606 session. On 16 Apr. Twyneho admitted that he was the chief beneficiary of the patent. He mounted a spirited defence on 28 Apr., but (if he can be believed) because some Members ‘imagined it to be made of wheat, and therefore unprofitable to the commonwealth’, the patent was condemned as a grievance on 10 May, though it remained in force until 1611.
