On the death of his elder brother in 1622, Boteler became the head of an ancient and prolific Hertfordshire family.
Boteler became a deputy lieutenant in 1623 on the recommendation of his father-in-law. He stood for Hertfordshire at the general election to Charles I’s first Parliament with the support of the lord lieutenant, the 2nd earl of Salisbury (William Cecil*), and was returned together with his cousin Sir John Boteler*.
As sheriff, in the spring of 1631, Boteler was obliged to certify the returns from the justices of the peace concerning the price of corn; he was dropped from the county bench shortly after completing his shrievalty, for causes that are not clear, and not restored until 1635.
