Wyse came from the junior branch of a substantial Devonshire family resident at Sydenham Damerel. His father had represented Bodmin in 1411 and 1422 and his uncle Oliver Wyse† had sat for Launceston in March 1416. Oliver had a son, also called Thomas, who died a minor before 1431, too young to have ever become active on the political stage.
Thomas was well qualified to see off these challenges, for like Fortescue he had received a legal training at the prestigious law school of Lincoln’s Inn. Before long, he found professional employment with some of the leading landowners in his native region. In 1427 he was named among the feoffees of Sir Thomas Beauchamp* of Whitelackington;
It may have been a combination of professional and personal contacts that saw Wyse elected to Parliament in 1427 as a Member for the Devon borough of Tavistock.
Wyse was not re-elected for either Tavistock or another constituency in 1429, although he attested the shire elections of that year. He returned to Parliament in 1432, by this time having attained sufficient standing to sit as knight of the shire. Now, however, there was a hiatus in his public career. By 1435 he had relinquished both of his posts as feodary, and he may have gone to fight in France, for in 1436 he was granted letters of attorney as about to go overseas, perhaps as a member of the earl of Devon’s retinue on the duke of Gloucester’s expedition for the relief of Calais.
Whether on account of his possible service at the siege of Calais, or by other means, Wyse had now come to the attention of the court, and before long he joined the ranks of the esquires of Henry VI’s chamber.
Wyse maintained important contacts in the south-west throughout the 1440s. He was retained by the citizens of Exeter, who in 1442 paid him 13s. 4d. for his advice on how to refuse to make a loan to the Crown, and who four years later admitted him to the freedom of the city as a reward for his good counsel, while the summer of 1445 saw him acting as a mainpernor for Nicholas, Baron Carew.
Since the 1430s Wyse had apparently maintained links with the Courtenay earl of Devon, although scarcely a hint of this survives in the records,
Wyse sensibly avoided taking up arms in the earl of Devon’s cause in 1455, when Courtenay sought to settle his score with Bonville once and for all. Nevertheless, the later 1450s were a troubled time in his career. In June 1457 a group of men headed by one James Radeclyf, clerk, was said to have stolen a valuable breviary worth as much as £10 from him at Northlew, and about the same time he was engaged in legal battles over unspecified trespasses with a number of men from Saltash who were said to have illicitly entered his property and taken a ship of his from Kenn.
Edward IV’s accession and the execution of the earl of Devon (the son of Wyse’s old patron, with whom he had formed an association in the final months of Henry VI’s reign), left Wyse, like other members of the Courtenay affinity, bereft of a master.
Furthermore, Wyse now also clashed with his wife’s kinsman by marriage, Martin Fortescue, and his wife Elizabeth, the only daughter and heir of his old opponent Richard Denshyll, over possession of the manor of Lamerton, two miles north-east of Sydenham. Martin was the only son of the chief justice’s second marriage, but their tenuous kinship mattered little to Wyse. Fortescue complained that although Elizabeth had rightfully inherited Lamerton from her father, Wyse and his brother John had come with a great number of armed men, expelled them and kept them out by patrolling the vicinity on horseback every day. They were indicted at the next session of the peace, but in spite of a judgement in Fortescue’s favour, the Wyses had retained the property and all but killed one of his servants.
At this late stage in life Wyse married a second time, taking as his new wife the widowed Isabel Whitelegh. Her late husband’s lands had been placed in the custody of the abbot of Tavistock during the minority of his heir, and Wyse and his wife were forced to sue for a third of the manors of Compton Giffard and Egg Buckland as her dower in the court of common pleas. In the event, the abbot proved no very formidable opponent and readily agreed to negotiate.
Henry VI’s Readeption in the autumn of 1470 might have brought Wyse to renewed prominence, not least because his first wife’s brother-in-law, Fortescue, had served as chancellor in exile to Margaret of Anjou, but in view of his advancing years he may have thought it prudent not to commit himself, and was certainly quick to secure a pardon from the restored Edward IV in December 1471. In the course of 1470-1 he (or a namesake) was in receipt of gifts of wine from the town authorities of Launceston (which had made him similar gifts 20 years previously), and it may therefore have been he who was commissioned to deliver the gaol at Launceston in December 1473.
