Edward Willoughby’s father, Francis, was the younger brother of Hugh Willoughby, 11th (CP 12th) Baron Willoughby of Parham, and a yeoman farmer with a tenancy at Willoughby Farm, Haigh, in Lancashire.
By May 1704, after the death of both his elder brother and his father, Edward found himself heir to his uncle Hugh Willoughby. He inherited the title from his childless uncle on 3 July 1712, just before Parliament was prorogued, and was quickly appointed a justice of the peace for Lancashire, though not initially to the quorum. He was closely linked to Sir Roger Bradshaigh‡, the leading landowner at Haigh, Member for Wigan and a supporter of the administration of Robert Harley, earl of Oxford. Willoughby appears to have been with Bradshaigh in London by November 1712, for on 18 Nov. Bradshaigh wrote to George Kenyon‡ that together with Willoughby he had recently had dinner with the chancellor of the duchy of Lancaster, William Berkeley, 4th Baron Berkeley of Stratton, when they had discussed Kenyon’s candidacy for the Wigan seat. Willoughby first sat in the House at the next opportunity available to him, on 13 Jan. 1713, a day of prorogation. He only attended the House two more times (on 3 and 17 Feb.), also prorogations, and failed to attend the next prorogation on 3 March.
The young and impoverished peer may have been targeted for recruitment to the Tories despite his whiggish family background. His close association with Bradshaigh suggests this, as does the royal warrant, dated 3 Mar. 1713, issued to pay Willoughby £400 as a ‘free gift and royal bounty’.
Willoughby’s death on the day after his 37th birthday took people by surprise, not least himself, as he died with his estate in disarray. The consistory court of Chester awarded the administration of his goods and chattels – which was valued as worth only £64 2s. 9d. – to his principal creditor, both his mother and his younger brother Charles, who inherited the title as 13th (CP 14th) Baron Willoughby of Parham, having renounced their claims to it.
