Hughes’s great-grandfather entered Parliament as knight of the shire for Middlesex in 1542; but little else can be discovered of Hughes’s background and upbringing except that his father was convicted for recusancy in 1584.
On his marriage in 1623, Hughes presumably leased Blyth Spital from Sir Gervase Clifton*, the husband of his cousin Frances Clifford. A few years later, after Frances died in childbirth, Hughes acted as sponsor at her daughter’s christening.
