The son of one of Northumberland’s leading gentlemen, Grey boasted two very distinguished godparents, the 1st Lord Burghley (Sir William Cecil†) and Queen Elizabeth’s cousin, Lord Hunsdon (Henry Carey†).
Two years later, Grey was elected to represent Northumberland in Parliament. Because of his baronetcy he was accorded the status of senior knight of the shire, a fact which offended his junior colleague, the older and much more experienced Sir Henry Widdrington. The latter even attacked Grey indirectly on 27 Apr. 1621, when he condemned the order of baronets, stating that ‘it grieved him to see skipjacks prank before men whose ancestors have gained place in the commonwealth and by blood’ simply on account of an honour that they had purchased.
Grey succeeded to his patrimony in September 1623. Two months later he was summoned before the Privy Council, after his servants were caught smuggling wool across the Scottish border, in breach of a royal Proclamation of 1622.
Grey was dismissed from most of his offices in 1627, apparently for opposing the Forced Loan, though he was quickly restored again once he made his peace with the Crown in the following year.
