The great-grandson of a London brewer who died in 1548, Nichols became a lawyer and made a fortunate marriage. His father-in-law, Sir George Bruce, one of the Scottish commissioners for the Union, was a brother of the 1st Lord Kinloss, master of the Rolls from 1603 until his death in 1611. Nichols clearly enjoyed a close relationship with the Bruce family. He stood squire to Kinloss’ heir when the latter was dubbed knight of the Bath at the creation of Prince Henry as the prince of Wales in 1610, and it was probably through Kinloss that he was also appointed a clerk of the Wards in the duchy of Cornwall. Although of similar name, there is no evidence that Nichols was related to Augustine Nicolls, the prince’s receiver-general.
Nichols was granted a pass for a visit to France in June 1613, presumably on family business.
Nichols was nominated for Bishop’s Castle at the general election of 1620 by Lord Cavendish (Sir William Cavendish I*), the son-in-law of the 1st Lord Kinloss.
Nichols was returned to Parliament again in 1624, this time for the duchy of Lancaster borough of Preston. He came in undoubtedly on the nomination of the chancellor, Sir Humphrey May, although the precise nature of his connection with either May or the duchy remains unclear. He received two committee appointments, one for a naturalization bill (15 Apr. 1624) and the other to ratify the transfer of York House to the Crown for the duke of Buckingham’s benefit (19 May).
