‘The everlasting Sir Compton Domvile’, as Lord Ellenborough, president of the India board, exasperated by yet another patronage request, cursed him in 1828, was a fixture in the Commons in this period.
He was a signatory to the petition of Irish noblemen and gentlemen against Catholic relief and voted in this sense, 6 Mar. 1827.
Plympton Erle was disfranchised by the Reform Act, and Domvile did not sit thereafter. He died in February 1857 and left the main family estates to his elder surviving son, Compton Charles William Domvile (1822-84), an army officer, requiring him (though not as an indispensable condition) to reside at Santry for at least four months a year. He devised an estate in county Mayo bought from the Trench family to his younger son, William Compton Domvile (1825-84).
