Keane was a substantial landowner, whose holdings centred on a 9,000 acre estate at Cappoquin, County Waterford. His father, Sir John Keane (1757-1829) had sat in the Irish and United Kingdom parliaments for Bangor (1791-7) and for Youghal (1797-1800, 1801-6, 1808-18) as a client of the earl of Shannon.
After the election, Keane attended Daniel O’Connell’s National Council in Dublin, but soon began to chart his own course, as a staunch whig.
Although Keane sat on a handful of election committees and presented a number of minor petitions, questions began to be raised in Ireland about his lack of activity at Westminster.
Keane faced criticism for his defence of landlord rights before the Devon Commission in 1843, yet he actively participated in famine relief work, as part of which he commissioned the construction of the Victoria Bridge at Cappoquin. He later joined a deputation on behalf of poor law guardians to request the remission of consolidated annuities incurred under the Labour-rate Act during the famine.
Keane died suddenly at the Waterford artillery barracks on 20 February 1855, while engaged in embodying his corps.
